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Richard D Smith Selected Research

Proteome

1/2021Nutritional markers and proteome in patients undergoing treatment for pulmonary tuberculosis differ by geographic region.
1/2018Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry.
1/2017Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease.
7/2016Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer.
3/2016Reproducibility of Differential Proteomic Technologies in CPTAC Fractionated Xenografts.
3/2016An Analysis of the Sensitivity of Proteogenomic Mapping of Somatic Mutations and Novel Splicing Events in Cancer.
1/2016Large-Scale and Deep Quantitative Proteome Profiling Using Isobaric Labeling Coupled with Two-Dimensional LC-MS/MS.
7/2014Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.
2/2014Metabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovani.
12/2013Approach to cerebrospinal fluid (CSF) biomarker discovery and evaluation in HIV infection.
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Richard D Smith Research Topics

Disease

48Neoplasms (Cancer)
12/2021 - 07/2003
31Infections
01/2022 - 06/2005
17Breast Neoplasms (Breast Cancer)
01/2021 - 07/2003
12Inflammation (Inflammations)
11/2020 - 10/2006
8Prostatic Neoplasms (Prostate Cancer)
11/2017 - 10/2010
7Diabetes Complications
07/2011 - 01/2007
6Type 2 Diabetes Mellitus (MODY)
03/2016 - 12/2006
5Obesity
04/2019 - 03/2014
5Alzheimer Disease (Alzheimer's Disease)
01/2019 - 07/2006
4Human Influenza (Influenza)
01/2017 - 11/2009
4Type 1 Diabetes Mellitus (Autoimmune Diabetes)
12/2016 - 02/2008
4Insulin Resistance
01/2016 - 11/2009
4Virus Diseases (Viral Diseases)
01/2014 - 11/2010
4HIV Infections (HIV Infection)
01/2014 - 01/2011
4Wounds and Injuries (Trauma)
08/2013 - 10/2006
4Neurodegenerative Diseases (Neurodegenerative Disease)
02/2009 - 07/2006
3Chromosomal Instability (Chromosome Stability)
01/2020 - 07/2016
3Overweight
01/2020 - 01/2019
3Chronic Disease (Chronic Diseases)
04/2019 - 02/2009
3Respiratory Tract Infections (Respiratory Tract Infection)
11/2018 - 07/2013
3Starvation
03/2014 - 11/2013
3Acute-Phase Reaction
06/2013 - 09/2010
3Lyme Disease (Disease, Lyme)
10/2012 - 04/2005
3Fibrosis (Cirrhosis)
07/2012 - 09/2007
3Disease Progression
03/2012 - 03/2007
3Autolysis
01/2011 - 04/2009
3Diabetes Mellitus
05/2008 - 01/2007
2COVID-19
01/2022 - 12/2020
2Pulmonary Tuberculosis
01/2021 - 01/2018
2Neoplasm Metastasis (Metastasis)
01/2021 - 05/2020
2Malaria
11/2020 - 09/2007
2Testicular Neoplasms (Testicular Cancer)
01/2020 - 01/2019
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 01/2020
2Noncommunicable Diseases
01/2019 - 11/2010
2Critical Illness (Critically Ill)
01/2019 - 06/2013
2Stroke (Strokes)
01/2019 - 01/2019
2Ovarian Neoplasms (Ovarian Cancer)
01/2019 - 01/2017
2Sepsis (Septicemia)
12/2017 - 01/2014
2Tuberculosis (Tuberculoses)
02/2016 - 09/2007
2Nephritis
01/2016 - 02/2014
2Mitochondrial Diseases (Mitochondrial Disease)
03/2014 - 03/2010
2Burns
06/2013 - 09/2010
2Retinoblastoma (Glioblastoma, Retinal)
07/2012 - 05/2008
2Acquired Immunodeficiency Syndrome (AIDS)
01/2011 - 09/2007
2Mpox (monkeypox)
12/2010 - 03/2008
2Smallpox (Variola)
12/2010 - 03/2008
2Parkinson Disease (Parkinson's Disease)
03/2010 - 07/2006
1Lung Diseases (Lung Disease)
01/2021
1Urinary Tract Infections (Urinary Tract Infection)
01/2021
1Brain Neoplasms (Brain Tumor)
12/2020
1Glioma (Gliomas)
12/2020
1Medulloblastoma
12/2020
1Ependymoma
12/2020
1Ganglioglioma
12/2020
1Craniopharyngioma (Craniopharyngiomas)
12/2020

Drug/Important Bio-Agent (IBA)

101Proteins (Proteins, Gene)FDA Link
01/2021 - 07/2003
33ProteomeIBA
01/2021 - 07/2003
30Biomarkers (Surrogate Marker)IBA
05/2020 - 07/2003
19Peptides (Polypeptides)IBA
01/2018 - 02/2005
12Biological ProductsIBA
12/2020 - 03/2007
11LipidsIBA
12/2021 - 08/2010
8Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 01/2013
7RNA (Ribonucleic Acid)IBA
12/2020 - 10/2013
7Glucose (Dextrose)FDA LinkGeneric
03/2014 - 12/2006
6Messenger RNA (mRNA)IBA
01/2017 - 07/2007
4Colistin (Coly-Mycin)FDA Link
01/2022 - 01/2021
4Phosphotransferases (Kinase)IBA
12/2020 - 07/2014
4SugarsIBA
01/2020 - 11/2010
4Fatty Acids (Saturated Fatty Acids)IBA
01/2019 - 09/2007
4Blood Proteins (Serum Proteins)IBA
01/2018 - 09/2010
4EnzymesIBA
12/2017 - 01/2010
4Phenobarbital (Luminal)FDA Link
12/2017 - 03/2016
4CytokinesIBA
11/2013 - 06/2012
4Complement System Proteins (Complement)IBA
06/2013 - 07/2010
3AntigensIBA
01/2022 - 01/2019
3DNA (Deoxyribonucleic Acid)IBA
10/2021 - 10/2013
3Pharmaceutical PreparationsIBA
01/2019 - 07/2014
3VaccinesIBA
01/2017 - 11/2009
3TrypsinIBA
01/2011 - 04/2009
3Glycated ProteinsIBA
02/2009 - 06/2007
2Guanosine Diphosphate (GDP)IBA
12/2020 - 01/2019
2MicroRNAs (MicroRNA)IBA
01/2020 - 10/2014
2Histones (Histone)IBA
01/2020 - 05/2014
2Amyloid (Amyloid Fibrils)IBA
01/2019 - 01/2018
2C-Reactive ProteinIBA
01/2018 - 07/2013
2Protein Isoforms (Isoforms)IBA
01/2017 - 10/2014
2Prostate-Specific Antigen (Semenogelase)IBA
12/2016 - 07/2013
2IsotopesIBA
01/2016 - 07/2007
2PhosphoproteinsIBA
07/2014 - 10/2003
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2013 - 01/2007
2FibrinolysinFDA Link
08/2013 - 10/2010
2Antiviral Agents (Antivirals)IBA
04/2013 - 07/2011
2Insulin (Novolin)FDA Link
07/2012 - 01/2007
2Virulence Factors (Pathogenicity Factors)IBA
06/2011 - 09/2006
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
03/2010 - 07/2006
1phosphorylethanolamine (phosphoethanolamine)IBA
01/2022

Therapy/Procedure

11Therapeutics
01/2021 - 01/2007
2Lasers (Laser)
01/2021 - 10/2010
2Prostatectomy (Retropubic Prostatectomy)
05/2020 - 10/2010
2Immunotherapy
01/2020 - 01/2020